What’s been Hapten-ing over the last 88 years? Fancy a historic look at the field of drug hypersensitivity? Well, here’s a fairly hefty review paper… Co-authored by the immunopharmacology team at the University of Liverpool (Xiaoli Meng, Paul Thomson, Dean Naisbitt) and Immunotoxicology Lead Sean Hammond from ApconiX, this [...]
Visyon is the ApconiX Charity for 2024 Visyon is a charity that supports the emotional health of children, young people and their families in the Cheshire East region of the UK where ApconiX is based. We got off to an early start and was raising money for Visyon in late 2023. So far we've [...]
ApconiX Welcomes Isabelle Heys ApconiX is delighted to welcome Isabelle Heys (she/they) who joins the ion channel laboratory team as an industry placement student and will be working with Dr Michael Morton and Dr Kimberly Rockley for the next 12 months. Career Isabelle is a second year student at [...]
It's Christmas! Really great time was had at the Christmas Do this year. As always such a laugh and everyone came home with a present - not always a good present - but a present all the same :) ...the Directors... ...Ruth's table... ...the other [...]
ApconiX Is Recruiting an Experimental Biologist The closing date for this job vacancy has passed. Please visit our Come and Join Us page for current vacancies. If you believe you have the skills and experience and would like to become part of our team please send your speculative CV to careers@apconix.com The Role [...]
Human Neuronal Cells: Possibilities in Drug Safety Testing and Beyond Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. Early detection of neurotoxicity induced by potential new therapies is a major challenge, and hiPSC-neuronal cells may provide a [...]
An Integrated Approach for Early In Vitro Seizure Prediction Utilising hiPSC Neurons and Human Ion Channel Assays ApconiX are delighted with our recent publication in Toxicological Sciences where we presented our new data on our integrated approach to detecting seizure. After 3 years of research, we launched the seizure [...]
The Reductionist Approach The hERG assay has been a mainstay of safety screening in drug discovery for the last 2 decades. Aided by the development of high throughput automated technology, this important assay has brought unparalleled progress in our ability to design safer drugs without those properties that may [...]
ApconiX Welcomes Joanne Wilson ApconiX is delighted to welcome Joanne Wilson who joins as a Project Manager and will be working with Dr Richard Knight. With over 20 years’ experience as a DMPK scientist and project manager at AstraZeneca, Jo has led cross-functional teams and driven the efficient development [...]
ApconiX Celebrates the Success of Two of Our Project Students ApconiX supervised two final year first degree students from the University of Birmingham this past academic year and caught up with them after their graduation. Edward Withnall and Tahera Yasmin were both supervised by Dr Sean Hammond, Immunotoxicology Lead. [...]
