ApconiX is delighted to be presenting a poster at ELRIG 2019 titled “Sodium channel selectivity of two anti-epileptic drugs.” The poster includes research started by our placement student Priscilla Dumenu. Dr Michael Morton, Dr Richard Knight, Dr Kimberly Rockley, Phumzile Sikakana and Olivia Turner are all attending the conference. “I am really looking forward to [...]
Professor Ruth Roberts, Co-Founder and Director of ApconiX will be speaking at the American Association of Pharmaceutical Scientists (AAPS) on Monday 4th November at 9:00am in a session entitled "Next Generation Technologies in Preclinical Development” chaired by Dr Shraddha Thakkar from the US FDA. Ruth’s talk is entitled “Science-Driven Design of the Preclinical Package: Case [...]
ApconiX welcomes Olivia Turner to the team. Olivia has just finished her second year studying Biomedical Sciences at The University of Sheffield and will be working at ApconiX as an industry placement student until Christmas. She will then join Aptus Clinical and continue her placement until the end of June. Choosing to take the Physiology [...]
Phumzile Sikakana talks about the final part of her Triple Half Marathon Challenge. “I took to the streets of south Manchester on Sunday the 13th of October to complete my final half marathon, making it 3 races in 6 weeks. Honestly, I had let my training slip since the start of the challenge, so I [...]
Dr Michael Morton, Director and Co-Founder will be speaking at the 10th Nanion User Meeting on Thursday 17th of October, "Two Years of Experience and Learning with Patchliner". The User Meeting is being held from Wednesday 17th to Thursday 18th of October at Nanion’s headquarters in Munich. Founded in 2002, Nanion has grown to be [...]
We were thrilled to welcome Jayne Ingram from Axion Biosystems into the ApconiX laboratory to conduct a pilot study using their Maestro Pro multielectrode array (MEA) system and Ncardia iPSC-derived neuronal cells. The cells were cultured for three weeks before Jayne arrived to allow the formation of neuronal networks, which would allow us to assess [...]
A thorough understanding of potential target-related effects is crucial to making the right choices in drug discovery. Experienced project toxicologists extract and interpret data from mouse knockouts, human gene mutations and known effects of modulators to determine the potential consequences of target inhibition or activation in each organ system. Target Safety Assessments are pivotal in [...]
On the 26th of September we hosted a Macmillan coffee at Alderley Park. It was a lovely morning where we all came together for a cuppa, some delicious home baking and a chat, all in aid of Macmillan Cancer Support. We had Pimm’s cupcakes, vegan carrot cake, lemon drizzle cake, banana loaf, individual Victoria sponges [...]
Phumzile Sikakana talks about part two of her Triple Half Marathon Challenge. “Last Sunday 22nd of September I ran the Macc-Fest Half Marathon in Macclesfield marking two-thirds of the way through my triple half marathon journey, and it was a hilly one! Although I didn’t manage to get a personal best, I was the 33rd [...]
Come and complete the questionnaire Dr Hitesh Mistry has developed to investigate whether expert interpretation of data is as good as complex computational modelling at the Safety Pharmacology Society Annual Meeting at Barcelona this week. ApconiX will have copies of the questionnaire on their stand number 307. Dr Hitesh Mistry is a computational modelling expert [...]
