Alderley Park Companies Receive Bionow Awards

Drs Michael Morton and Richard Knight thoroughly enjoyed the Bionow 2018 Awards Dinner at the Mere Golf Resort & Spa, Cheshire on 29th November. The awards which recognise excellence, outstanding achievement and enterprise in a sector that is worth more than £13bn to the North’s economy, were sponsored by Manchester Science Partnerships, Alderley Park, Appleyard [...]

By |2018-12-16T19:10:57+00:00December 16th, 2018|Events|Comments Off on Alderley Park Companies Receive Bionow Awards

ApconiX Welcomes Dr Karin Burnett to The Team.

ApconiX is delighted to welcome Dr Karin Burnett, an experienced project toxicologist with a broad knowledge of toxicology and chemical risk assessment in the pharmaceutical industry.  Karin will join the team of experts in nonclinical safety toxicology at ApconiX, who cover all major safety disciplines and are committed to advancing the science of drug safety. Karin [...]

By |2018-11-28T16:37:14+00:00December 12th, 2018|Target Safety Assessments, Careers|Comments Off on ApconiX Welcomes Dr Karin Burnett to The Team.

Highlight Article for Experimental Biology and Medicine

“Drug discovery and development: Biomarkers of neurotoxicity and neurodegeneration”, co-authored by Abigail L Walker, Syed Z Imam and  Ruth A Roberts, has been selected as a highlight article for Experimental Biology and Medicine’s 243:13 issue. As a result of this designation it will be open access for 90 days. Click here to access Abstract The [...]

By |2018-12-06T13:53:13+00:00December 7th, 2018|Publications|Comments Off on Highlight Article for Experimental Biology and Medicine

ApconiX Welcomes Phumzile Sikakana to The Team.

ApconiX is delighted to welcome Phumzile Sikakana who joins us straight from University.  Phum, an enthusiastic new masters graduate will work with our team of experienced scientists on a variety of projects, including target safety reviews and in the ion channel screening laboratory, helping our clients make better decisions on drug safety. Phum studied Biomedical [...]

By |2018-11-30T09:11:38+00:00December 5th, 2018|Target Safety Assessments, Careers|Comments Off on ApconiX Welcomes Phumzile Sikakana to The Team.

Insider Breakfast Golden Triangle Breakfast Event

Professor Ruth Roberts was thrilled to be invited to speak at Business Insider’s recent Golden Triangle Breakfast Event at Alderley Park in the Northwest.  The new golden triangle is part of a vision to take the Cheshire Science Corridor and create a golden triangle in the Northwest to rival the original golden triangle of Oxford, [...]

By |2018-11-28T16:41:51+00:00November 29th, 2018|Events|Comments Off on Insider Breakfast Golden Triangle Breakfast Event

Making safety a part of drug design

The Global Antibiotic R&D Partnership (GARDP) will host a live webinar with ApconiX's Dr Claire Sadler on ''Making safety a part of drug design" on 13th November 16.00-17.30 GMT.  Claire is an expert discovery project toxicologist specialising in early project safety assessment and risk mitigation.  In this webinar, she discusses the toxicological challenges and pitfalls [...]

By |2018-11-08T13:12:06+00:00November 2nd, 2018|Events|Comments Off on Making safety a part of drug design

Target Safety Reports: What’s in a Name?

Irrespective of what we call them, target safety reports form a key part of risk assessment and risk mitigation plans in drug discovery and development. Why is that?  Well, target-related toxicity accounts for >50% of all drug project failures (Cook et al., 2014) so it’s vital to understand the potential unintended consequences of target modulation.  [...]

By |2018-10-12T14:15:50+00:00October 12th, 2018|Target Safety Assessments|Comments Off on Target Safety Reports: What’s in a Name?

ApconiX Welcomes Bethany Russell

Bethany joins ApconiX as a placement student for part of September.  A second-year student, Bethany is studying Biomedical Sciences at Sheffield University.  Her degree is a four-year sandwich course, with a third-year placement in industry. Bethany was unsure if a career in a laboratory was for her and wanted to be clearer before making her [...]

By |2018-11-28T15:30:09+00:00October 4th, 2018|Ion Channels, Careers|Comments Off on ApconiX Welcomes Bethany Russell

Collaboration and competition: ethics in toxicology

What are our attitudes to research resourcing, publication and the peer review system?  The British Toxicology Society (BTS) is conducting a survey to establish attitudes of toxicologists to key questions such as ‘I believe collaboration to be important in driving toxicology research in the UK’ and ‘I believe the current system of peer review for [...]

By |2018-11-28T15:34:59+00:00September 27th, 2018|Toxicology|Comments Off on Collaboration and competition: ethics in toxicology

ApconiX is supporting PhysioStim at SPS

ApconiX and PhysioStim will be celebrating their first year of The European Centre of Excellence for preclinical cardiovascular electrophysiology at the Safety Pharmacology Society Annual Meeting in Washington this September.  ApconiX will be supporting PhysioStim as they exhibit at the Marriott Wardman Park Hotel on Stand 412 from the 30th of September to the 3rd [...]

By |2018-09-25T18:23:43+00:00September 26th, 2018|Ion Channels, Events|Comments Off on ApconiX is supporting PhysioStim at SPS