Innovative Models for In Vitro Detection of Seizure

ApconiX is delighted that Dr Kim Rockley's article ‘ Innovative models for in vitro detection of seizure‘ has now been accepted for publication in Toxicology Research. The article highlights how new technologies such as microelectrode array and ion channel screening offer the opportunity to screen for seizure liability in vitro, avoiding costly failures in preclinical [...]

By |2019-11-20T15:45:04+00:00November 20th, 2019|Ion Channels, Publications|Comments Off on Innovative Models for In Vitro Detection of Seizure

Dr Michael Morton Is Presenting at 10th Nanion Annual User Meeting

Dr Michael Morton, Director and Co-Founder will be speaking at the 10th  Nanion User Meeting on Thursday 17th of October, "Two Years of Experience and Learning with Patchliner".  The User Meeting is being held from Wednesday 17th to Thursday 18th of October at Nanion’s headquarters in Munich. Founded in 2002, Nanion has grown to be [...]

By |2019-10-13T17:50:37+01:00October 13th, 2019|Ion Channels, Events|Comments Off on Dr Michael Morton Is Presenting at 10th Nanion Annual User Meeting

ApconiX Conduct Pilot Study with Axion Biosystems

We were thrilled to welcome Jayne Ingram from Axion Biosystems into the ApconiX laboratory to conduct a pilot study using their Maestro Pro multielectrode array (MEA) system and Ncardia iPSC-derived neuronal cells.  The cells were cultured for three weeks before Jayne arrived to allow the formation of neuronal networks, which would allow us to assess [...]

By |2019-10-10T10:10:14+01:00October 10th, 2019|Ion Channels, Toxicology|Comments Off on ApconiX Conduct Pilot Study with Axion Biosystems

ApconiX Are in Boston, USA at the End of August

Dr Richard Knight and Professor Ruth Roberts are travelling to Boston at the end of August to meet with old colleagues and new contacts, promoting the company’s services in Project Toxicology, Ion Channel Screening and Assay Development, Target Safety Assessments and all aspects of Nonclinical Programme Design. They will be joined by Dr Andrew Winkley. [...]

By |2019-08-20T17:40:25+01:00August 20th, 2019|Ion Channels, Target Safety Assessments, Toxicology, Events|Comments Off on ApconiX Are in Boston, USA at the End of August

The Reductionist Approach

The hERG assay has been a mainstay of safety screening in drug discovery for the last 2 decades. Aided by the development of high throughput automated technology, this important assay has brought unparalleled progress in our ability to design safer drugs without those properties that may lead to life-threatening cardiac arrhythmia. In a series of [...]

By |2019-07-24T14:41:23+01:00July 11th, 2019|Ion Channels|Comments Off on The Reductionist Approach

ApconiX Welcomes Priscilla Dumenu

ApconiX is delighted to welcome Priscilla Dumenu for a 2-week placement.  Priscilla will be working alongside Dr Michael Morton and Dr Karen Jones in the Ion Channel laboratory. Priscilla has just finished her second year studying Pharmacy at the University of Manchester.  The 5-year integrated master’s degree includes a placement year in a community or [...]

By |2019-06-28T18:12:07+01:00June 28th, 2019|Ion Channels, Careers|Comments Off on ApconiX Welcomes Priscilla Dumenu

Sophion’s Ion Channel Modulation Symposium

Dr Michael Morton will be attending Sophion’s Ion Channel Modulation Symposium, on the 19th to 20th of June 2019, at Clare College in Cambridge, UK. Sophion was founded almost twenty years ago by a group of passionate electrophysiologists and offers the some of the most flexible automated patch clamp systems on the market today. The [...]

By |2019-06-07T10:18:56+01:00June 12th, 2019|Ion Channels, Events|Comments Off on Sophion’s Ion Channel Modulation Symposium

ApconiX Joins the MDC’s Virtual R&D platform

ApconiX has joined the Medicines Discovery Catapult’s Virtual R&D platform.  This is a unique national network of consultants, private sector CROs, expert labs and public sector centres of excellence, providing medicines discovery expertise, services and virtual programme management. ApconiX specialises in ion channel biology, target safety assessments and in all aspects of nonclinical programme design [...]

By |2019-06-07T10:20:14+01:00June 6th, 2019|Ion Channels|Comments Off on ApconiX Joins the MDC’s Virtual R&D platform

ApconiX Welcomes Sushma Pabbineedi.

ApconiX is delighted to welcome Sushma Pabbineedi for a placement during May.  Sushma will be working alongside Dr Michael Morton and Dr Karen Jones in the ion channel laboratory. Sushma studied Biomedical Sciences and gained a bachelor’s degree from Manchester Metropolitan University.  She took a gap year working at the AQA examination board in Manchester [...]

By |2019-05-09T12:14:32+01:00May 9th, 2019|Ion Channels, Careers|Comments Off on ApconiX Welcomes Sushma Pabbineedi.