Our Ion Channel Laboratory

ApconiX’s ion channel laboratory brings together ion channel screening, microelectrode array (MEA) services and in silico modelling to support informed decisions in drug discovery and safety assessment.

Explore our New Approach Methodologies (NAMs) services below to find the most relevant route for your programme.

Overview of services

Select a service below to explore our NAMs capabilities

Automated Patch Clamp

Functional Assessment of Ion Channel Activity

Microelectrode Array

Assessment of the Activity of Human iPSC Derived Neurons

What Are NAMs?

Explore Human Relevant In Vitro Safety Methods

Cardiac Safety

Identify Cardiac Risks in Discovery and Development

CNS Safety

Identify CNS Risks in Discovery and Development

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Customer Focus

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Rapid turnaround

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Putting data into context

Cardiac Safety

hERG

Rapid High Quality Functional hERG Screening

CiPA

Comprehensive in vitro Proarrhythmia Assay

In Silico

In Silico Cardiac Safety Modelling

Cardiac MEA

Human IPSC Micro Electrode Array

Supporting safe cardiovascular drug discovery and development with expert insight and advanced models

CNS Safety

Seizure Panel

Ion Channel Liability Assessment.

Seizure MEA

Human IPSC Micro Electrode Array

Sedation Panel

Ion Channel Liability Assessment

Sedation MEA

Human IPSC Micro Electrode Array

CNS Liability

Ion Channel Liability Assessment

Comprehensive CNS safety evaluation combining in vitro ion channel measurements by automated patch clamp and MEA (Micro Electrode

Array)

Vascular Panel

Ion Channel Liability Assessment

Pain MEA

Screening of Analgesic Compounds.

SAR

Structure Activity Relationship

Recovery From Block

Novel Approaches to Sodium Ion Channel Measurements

Manual Patch Clamp

Gold Standard Ion Channel Measurements