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About Michael Morton

Dr Michael Morton, PhD, Director and Cofounder, ApconiX, UK, an integrated toxicology and ion channel company that brings together a team of world-renowned nonclinical safety experts with over 400 years of drug discovery and development experience. Mike graduated from the University of Wolverhampton with a degree in Biomedical Sciences and then aspiration to work in hospital pathology. Having finished his Sandwich placement in Clinical Biochemistry at Sandwell Hospital and Mike subsequently gained a MSc in Clinical Biochemistry from the University of Manchester and carried out research into porphyrin metabolism. Moving to the University of Leeds, Mike completed his PhD in Pharmacology at researching adenosine receptor expression in the rat kidney . Mike was introduced to ion channels as a Post-Doc at Leeds and Yale University, patching with the likes of Fred Sigworth and Steve Hebert, then joined the Global Ion Channel Initiative at AstraZeneca. Mike worked at AstraZeneca for eight years before founding ApconiX with Professor Ruth Roberts and Dr Richard Knight. Mike has a serious passion for ion channels. And he’s very good at them . He is a serious scientist (with a serious sense of humour) who wants to make sure that every customer understands the consequences of the results he obtains and works with his colleagues to ensure a better decision is made on drug safety.

ApconiX Welcomes Sushma Pabbineedi.

ApconiX is delighted to welcome Sushma Pabbineedi for a placement during May.  Sushma will be working alongside Dr Michael Morton and Dr Karen Jones in the ion channel laboratory. Sushma studied Biomedical Sciences and gained a bachelor’s degree from Manchester Metropolitan University.  She took a gap year working at the AQA examination board in Manchester [...]

By |2019-05-09T12:14:32+01:00May 9th, 2019|Ion Channels, Careers|Comments Off on ApconiX Welcomes Sushma Pabbineedi.

30th Symposium on Medicinal Chemistry in Eastern England

Dr Michael Morton will be attending the 30th Symposium on Medicinal Chemistry in Eastern England at Hatfield, United Kingdom on 2nd May 2019. This is a highly successful, long-standing, one-day annual meeting. To commemorate 30 years, the programme will focus on ‘Celebrating UK Drug Discovery’, highlighting success stories from large pharma, biotech and academia; and [...]

By |2019-04-24T14:56:18+01:00April 25th, 2019|Ion Channels, Events|Comments Off on 30th Symposium on Medicinal Chemistry in Eastern England

K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall

Dr Michael Morton co-authored a paper recently published in the Journal of Cardiovascular Electrophysiology. The paper should serve as a reminder that ion channels which may not be the focus of regulatory guidance or the latest CiPA initiative, still play a critical role in cardiac function, and shouldn’t be forgotten. TASK‐1 (K2P3.1) is a member [...]

By |2019-04-18T10:09:25+01:00April 18th, 2019|Ion Channels, Publications|Comments Off on K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall

SOT 58th Annual Meeting & ToxExpo – 2588: Talk by Dr Michael Morton of ApconiX

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, Dr Michael Morton of ApconiX will be giving a talk as part of the workshop "Can we panelize seizure?".  On Wednesday March 13th 9:30am – 10:00am in the Convention Center Ballroom III.  An Innovations in Applied [...]

By |2019-03-06T11:22:16+01:00March 6th, 2019|Ion Channels, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 2588: Talk by Dr Michael Morton of ApconiX

SOT 58th Annual Meeting & ToxExpo – 2072: Poster Presentation by Richard Printemps of PhysioStim

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation by Richard Printemps of PhysioStim on Tuesday March 12th 3:00pm - 4:30pm Poster Board P463 Convention Center Exhibition Hall.  Incorporating the CiPA Paradigm into an Integrated Cardiac Risk Assessment. Authors:  M. Morton1, R. Printemps2, M. [...]

By |2019-03-05T14:42:32+01:00March 5th, 2019|Ion Channels, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 2072: Poster Presentation by Richard Printemps of PhysioStim

ApconiX Welcomes Dr Steffen Ernst

ApconiX is delighted to welcome Dr Steffen Ernst to our team, as the company begins its international expansion with the formation of its Swedish subsidiary, ApconiX AB. Steffen has worked in preclinical and clinical safety for over 20 years with Hoechst-Schering, Boehringer-Ingelheim, AstraZeneca, Pfizer and Ipsen, holding various pre-clinical and clinical positions of ever-increasing responsibility [...]

By |2019-02-07T16:37:23+01:00February 6th, 2019|Toxicology, Careers|Comments Off on ApconiX Welcomes Dr Steffen Ernst

Professor Ruth Roberts Becomes an Honorary Fellow of the British Toxicology Society

ApconiX are delighted to learn that the BTS Executive Committee has elected Professor Ruth Roberts as Honorary Fellow of the British Toxicology Society (hon FBTS) in recognition of her outstanding contribution to the science and profession of Toxicology, including to the BTS. Ruth commented “It’s such an honour to be recognised in this way by [...]

By |2019-01-30T15:27:43+01:00January 31st, 2019|Toxicology, Events, Uncategorised|Comments Off on Professor Ruth Roberts Becomes an Honorary Fellow of the British Toxicology Society

Alderley Park Companies Receive Bionow Awards

Drs Michael Morton and Richard Knight thoroughly enjoyed the Bionow 2018 Awards Dinner at the Mere Golf Resort & Spa, Cheshire on 29th November. The awards which recognise excellence, outstanding achievement and enterprise in a sector that is worth more than £13bn to the North’s economy, were sponsored by Manchester Science Partnerships, Alderley Park, Appleyard [...]

By |2018-12-16T19:10:57+01:00December 16th, 2018|Events|Comments Off on Alderley Park Companies Receive Bionow Awards

ApconiX Welcomes Bethany Russell

Bethany joins ApconiX as a placement student for part of September.  A second-year student, Bethany is studying Biomedical Sciences at Sheffield University.  Her degree is a four-year sandwich course, with a third-year placement in industry. Bethany was unsure if a career in a laboratory was for her and wanted to be clearer before making her [...]

By |2018-11-28T15:30:09+01:00October 4th, 2018|Ion Channels, Careers|Comments Off on ApconiX Welcomes Bethany Russell

ApconiX is supporting PhysioStim at SPS

ApconiX and PhysioStim will be celebrating their first year of The European Centre of Excellence for preclinical cardiovascular electrophysiology at the Safety Pharmacology Society Annual Meeting in Washington this September.  ApconiX will be supporting PhysioStim as they exhibit at the Marriott Wardman Park Hotel on Stand 412 from the 30th of September to the 3rd [...]

By |2018-09-25T18:23:43+01:00September 26th, 2018|Ion Channels, Events|Comments Off on ApconiX is supporting PhysioStim at SPS