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About Michael Morton

Dr Michael Morton, PhD, Director and Cofounder, ApconiX, UK, an integrated toxicology and ion channel company that brings together a team of world-renowned nonclinical safety experts with over 400 years of drug discovery and development experience. Mike graduated from the University of Wolverhampton with a degree in Biomedical Sciences and then aspiration to work in hospital pathology. Having finished his Sandwich placement in Clinical Biochemistry at Sandwell Hospital and Mike subsequently gained a MSc in Clinical Biochemistry from the University of Manchester and carried out research into porphyrin metabolism. Moving to the University of Leeds, Mike completed his PhD in Pharmacology at researching adenosine receptor expression in the rat kidney . Mike was introduced to ion channels as a Post-Doc at Leeds and Yale University, patching with the likes of Fred Sigworth and Steve Hebert, then joined the Global Ion Channel Initiative at AstraZeneca. Mike worked at AstraZeneca for eight years before founding ApconiX with Professor Ruth Roberts and Dr Richard Knight. Mike has a serious passion for ion channels. And he’s very good at them . He is a serious scientist (with a serious sense of humour) who wants to make sure that every customer understands the consequences of the results he obtains and works with his colleagues to ensure a better decision is made on drug safety.

ApconiX Welcomes Priscilla Dumenu

ApconiX is delighted to welcome Priscilla Dumenu for a 2-week placement.  Priscilla will be working alongside Dr Michael Morton and Dr Karen Jones in the Ion Channel laboratory. Priscilla has just finished her second year studying Pharmacy at the University of Manchester.  The 5-year integrated master’s degree includes a placement year in a community or [...]

By |2019-06-28T18:12:07+01:00June 28th, 2019|Ion Channels, Careers|Comments Off on ApconiX Welcomes Priscilla Dumenu

ApconiX Welcomes Rosie Tennant

ApconiX is delighted to welcome Rosie Tennant, who joins us for work experience this week.  Rosie will be working with Dr Michael Morton and Dr Karen Jones in the ion channel laboratory. Rosie is in Year 12 at The Fallibroome Academy, a secondary and sixth form college in Macclesfield.  Studying A level biology, chemistry and [...]

By |2019-06-15T09:29:13+01:00June 14th, 2019|Careers|Comments Off on ApconiX Welcomes Rosie Tennant

Sophion’s Ion Channel Modulation Symposium

Dr Michael Morton will be attending Sophion’s Ion Channel Modulation Symposium, on the 19th to 20th of June 2019, at Clare College in Cambridge, UK. Sophion was founded almost twenty years ago by a group of passionate electrophysiologists and offers the some of the most flexible automated patch clamp systems on the market today. The [...]

By |2019-06-07T10:18:56+01:00June 12th, 2019|Ion Channels, Events|Comments Off on Sophion’s Ion Channel Modulation Symposium

ApconiX Joins the MDC’s Virtual R&D platform

ApconiX has joined the Medicines Discovery Catapult’s Virtual R&D platform.  This is a unique national network of consultants, private sector CROs, expert labs and public sector centres of excellence, providing medicines discovery expertise, services and virtual programme management. ApconiX specialises in ion channel biology, target safety assessments and in all aspects of nonclinical programme design [...]

By |2019-06-07T10:20:14+01:00June 6th, 2019|Ion Channels|Comments Off on ApconiX Joins the MDC’s Virtual R&D platform

ApconiX Welcomes Sushma Pabbineedi.

ApconiX is delighted to welcome Sushma Pabbineedi for a placement during May.  Sushma will be working alongside Dr Michael Morton and Dr Karen Jones in the ion channel laboratory. Sushma studied Biomedical Sciences and gained a bachelor’s degree from Manchester Metropolitan University.  She took a gap year working at the AQA examination board in Manchester [...]

By |2019-05-09T12:14:32+01:00May 9th, 2019|Ion Channels, Careers|Comments Off on ApconiX Welcomes Sushma Pabbineedi.

30th Symposium on Medicinal Chemistry in Eastern England

Dr Michael Morton will be attending the 30th Symposium on Medicinal Chemistry in Eastern England at Hatfield, United Kingdom on 2nd May 2019. This is a highly successful, long-standing, one-day annual meeting. To commemorate 30 years, the programme will focus on ‘Celebrating UK Drug Discovery’, highlighting success stories from large pharma, biotech and academia; and [...]

By |2019-04-24T14:56:18+01:00April 25th, 2019|Ion Channels, Events|Comments Off on 30th Symposium on Medicinal Chemistry in Eastern England

K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall

Dr Michael Morton co-authored a paper recently published in the Journal of Cardiovascular Electrophysiology. The paper should serve as a reminder that ion channels which may not be the focus of regulatory guidance or the latest CiPA initiative, still play a critical role in cardiac function, and shouldn’t be forgotten. TASK‐1 (K2P3.1) is a member [...]

By |2019-04-18T10:09:25+01:00April 18th, 2019|Ion Channels, Publications|Comments Off on K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall

SOT 58th Annual Meeting & ToxExpo – 2588: Talk by Dr Michael Morton of ApconiX

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, Dr Michael Morton of ApconiX will be giving a talk as part of the workshop "Can we panelize seizure?".  On Wednesday March 13th 9:30am – 10:00am in the Convention Center Ballroom III.  An Innovations in Applied [...]

By |2019-03-06T11:22:16+01:00March 6th, 2019|Ion Channels, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 2588: Talk by Dr Michael Morton of ApconiX

SOT 58th Annual Meeting & ToxExpo – 2072: Poster Presentation by Richard Printemps of PhysioStim

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation by Richard Printemps of PhysioStim on Tuesday March 12th 3:00pm - 4:30pm Poster Board P463 Convention Center Exhibition Hall.  Incorporating the CiPA Paradigm into an Integrated Cardiac Risk Assessment. Authors:  M. Morton1, R. Printemps2, M. [...]

By |2019-03-05T14:42:32+01:00March 5th, 2019|Ion Channels, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 2072: Poster Presentation by Richard Printemps of PhysioStim

ApconiX Welcomes Dr Steffen Ernst

ApconiX is delighted to welcome Dr Steffen Ernst to our team, as the company begins its international expansion with the formation of its Swedish subsidiary, ApconiX AB. Steffen has worked in preclinical and clinical safety for over 20 years with Hoechst-Schering, Boehringer-Ingelheim, AstraZeneca, Pfizer and Ipsen, holding various pre-clinical and clinical positions of ever-increasing responsibility [...]

By |2019-02-07T16:37:23+01:00February 6th, 2019|Toxicology, Careers|Comments Off on ApconiX Welcomes Dr Steffen Ernst