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About Ruth Roberts

Professor Ruth A Roberts, PhD, ATS, FBTS, ERT, FRSB, FRCPath Director and Cofounder, ApconiX, UK and Chair and Director of Drug Discovery, University of Birmingham, UK Ruth is chair of drug discovery at Birmingham University, UK and Cofounder of ApconiX, an integrated toxicology and ion channel company that brings together a team of world-renowned nonclinical safety experts with over 400 years of drug discovery and development experience. Previously, Ruth was Global Head of Regulatory Safety at AstraZeneca and Director of Toxicology for Aventis. Ruth is an established science professional bringing rigorous expert thinking to toxicology, drug discovery and drug development. With >140 publications in peer reviewed journals, she is focused on reducing attrition attributable to safety and toxicity. A former president of the British Toxicology Society, former president of EUROTOX, former secretary to SOT and president elect of the Academy of Toxicological Sciences, Ruth was the recipient of the SOT Achievement award in 2002, the EUROTOX Bo Holmstedt Award in 2009 and the SOT Founders award in 2018 for outstanding leadership in toxicology.

British Toxicology Society Congress a Great Success

Dr Richard Knight, Dr Guy Healing, Professor Ruth Roberts, Phumzile Sikakana and Dr Karin Burnett thoroughly enjoyed the British Society of Toxicology Congress this week at Robinson College, University of Cambridge. Highlights of the meeting included a great opening keynote from Dr Stefan Platz (AstraZeneca) who shared his vision for the use of AI in [...]

By |2019-04-18T10:14:42+01:00April 18th, 2019|Toxicology, Events|Comments Off on British Toxicology Society Congress a Great Success

Toxicogenomics: A 2020 Vision

Together with the promotion of non-animal testing, in vitro toxicogenomics (TGx) may play a vital role in the next generation risk assessment paradigm. A strategic shift in risk assessment provides an unprecedented opportunity for repositioning TGx in the regulatory setting. As the emerging technique continues to impact the TGx field, novel genomic features such as [...]

By |2019-04-17T15:54:02+01:00April 17th, 2019|Toxicology, Publications|Comments Off on Toxicogenomics: A 2020 Vision

ApconiX Attends British Toxicology Society Congress – “Celebrating 40 years of the BTS”.

British Toxicology Society (BTS) and the UK Environmental Mutagen Society Annual Congress “Celebrating 40 years of the BTS" will be held at Robinson College, University of Cambridge between 15th -17th of April. Professor Ruth Roberts, Dr Richard Knight, Dr Guy Healing and Phumzile Sikakana will all be attending.  Ruth will be presented with an Honorary Fellowship [...]

By |2019-04-14T16:01:01+01:00April 14th, 2019|Toxicology, Events|Comments Off on ApconiX Attends British Toxicology Society Congress – “Celebrating 40 years of the BTS”.

Congratulations to Dr Myrtle Davis

The ApconiX team would like to congratulate Dr Myrtle Davis for becoming Vice President-Elect of the Society of Toxicology. Dr Davis is an executive director at Bristol-Myers Squibb, where she leads discovery toxicology in pharmaceutical candidate optimization to provide target and molecular hazard identification and risk assessments for issues identified in discovery research. She also [...]

By |2019-03-25T20:18:23+01:00March 27th, 2019|Events|Comments Off on Congratulations to Dr Myrtle Davis

Successful DMDG Symposium at Alderley Park

The DMDG Symposium at Alderley Park was a great success.  Organised by the teams from Sygnature, Alderley Park and ApconiX, over 120 delegates from around the country joined the symposium Dx Toxicology: Strategies for Success in Discovery and Development, focusing on asking the right questions at the right time around Target, Chemistry and Patient. Speakers [...]

By |2019-03-25T20:09:21+01:00March 26th, 2019|Target Safety Assessments, Events|Comments Off on Successful DMDG Symposium at Alderley Park

SOT 58th Annual Meeting & ToxExpo – 3575: a Late Breaking Poster Presentation

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation on Thursday 14th 8:30am - 11:30am Poster Board P372 Convention Center Exhibition Hall.  Circulating Biomarkers of Neurotoxicity: Identifying Fluidic Endpoints Correlating with Central Nervous System Toxicity in a Rodent Model of Neurotoxicity. Authors: [...]

By |2019-03-10T10:20:00+01:00March 8th, 2019|Toxicology, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 3575: a Late Breaking Poster Presentation

SOT 58th Annual Meeting & ToxExpo – 1455: Poster Presentation Sponsored by Professor Ruth Roberts

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation on Monday March 11th 10:45am - 12:15pm Poster Board P524 Convention Center Exhibition Hall sponsored by Professor Ruth Roberts.  Real-Time Measurement of Drug Release Using Carbon Nanotube MEA System. Authors:  N. Matsuda, A. Odawara, K. Ogawa, [...]

By |2019-03-08T16:23:39+01:00March 8th, 2019|Toxicology, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 1455: Poster Presentation Sponsored by Professor Ruth Roberts

SOT 58th Annual Meeting & ToxExpo – 1449: Poster Presentation Sponsored by Professor Ruth Roberts

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation on Monday March 11th 10:45am - 12:15pm Poster Board P518 Convention Center Exhibition Hall sponsored by Professor Ruth Roberts.  TRP Channel Responses in Human iPSC-Derived Sensory Neurons Using MEA System. Authors:  A. Odawara, Y. Kobayashi, N. [...]

By |2019-03-08T16:28:07+01:00March 8th, 2019|Toxicology, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 1449: Poster Presentation Sponsored by Professor Ruth Roberts

SOT 58th Annual Meeting & ToxExpo – 1448: Poster Presentation Sponsored by Professor Ruth Roberts

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation on Monday March 11th 10:45am - 12:15pm Poster Board P517 Convention Center Exhibition Hall sponsored by Professor Ruth Roberts.  Classification of Drug-Induced Seizure-Like Activities in Cultured Human iPSC-Derived Neurons. Authors:  Y. Ishibashi, A. Odawara, N. Matsuda, [...]

By |2019-03-08T16:29:21+01:00March 8th, 2019|Toxicology, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 1448: Poster Presentation Sponsored by Professor Ruth Roberts

SOT 58th Annual Meeting & ToxExpo – 1811: Poster Presentation by Dr Zhichao Liu of the FDA NCTR

At the Society of Toxicology 58th Annual Meeting and ToxExpo from March 10th to 14th at the Baltimore Convention Center, poster presentation by Dr Zhichao Liu of the FDA NCTR on Tuesday March 12th 1:30pm - 3:00pm Poster Board P190 Convention Center Exhibition Hall.  Repurposing Immortalized Cell Line-Based Transcriptomic Profiling Assays for Drug-Induced Liver Injury [...]

By |2019-03-08T16:19:01+01:00March 7th, 2019|Toxicology, Events|Comments Off on SOT 58th Annual Meeting & ToxExpo – 1811: Poster Presentation by Dr Zhichao Liu of the FDA NCTR