ApconiX Toxicology Archives
Alleviating the Long-term Cardiotoxicity of Cancer Therapies Kimberly Rockley completed her PhD in the Division of Pharmacy at Durham University before joining us at ApconiX in June last year. Her research utilised in vitro cardiomyocyte models to investigate the link between angiotensin signalling and anthracycline-induced cardiotoxicity. Here she describes [...]
ApconiX Conduct Pilot Study with Axion Biosystems We were thrilled to welcome Jayne Ingram from Axion Biosystems into the ApconiX laboratory to conduct a pilot study using their Maestro Pro microelectrode array (MEA) system and Ncardia iPSC-derived neuronal cells. The cells were cultured for three weeks before Jayne arrived [...]
ApconiX Are in Boston, USA at the End of August Dr Richard Knight and Professor Ruth Roberts are travelling to Boston at the end of August to meet with old colleagues and new contacts, promoting the company’s services in Project Toxicology, Ion Channel Screening and Assay Development, Target Safety [...]
Derisking projects: how a focus on TCP (Target – Chemistry – Patient) can help. We all know drug projects fail – so how can we improve our probability of success? TCP offers a systematic approach to de-risking projects by asking the right questions at the right time around target, [...]
Dr Kimberly Rockley Wins EUROTOX Fellowship Grant ApconiX was delighted to hear that Dr Kimberly Rockley had received a EUROTOX Fellowship Grant to attend the Gordon Research Seminar and Conference in the USA this August. The Cellular and Molecular Mechanisms of Toxicity Conference “Integration of Emerging Technologies in Mechanistic and Translational [...]
ApconiX Welcomes Dr Kimberly Rockley. ApconiX is delighted to welcome Dr Kimberly Rockley. Kim has a strong research background in oncology and will work with the team of experts in nonclinical safety and toxicology at ApconiX. Kim studied Biomedical Science and gained her bachelor’s degree and her master’s degree [...]
ApconiX Meet with the Servier Nonclinical Safety Team in Paris Professor Ruth Roberts and Dr Paul Duffy recently spent some time with the Servier nonclinical safety team in Paris, hosted by Dr Nancy Claude, Director of Non-Clinical Safety at Servier and Patrick Genissel, Director Centre of Excellence Research & [...]
Practical Application of Toxicology in Drug Development Professor Ruth Roberts, Co-founder and Director of ApconiX will be joining Rob Wallis and other eminent scientists in delivering training at the highly acclaimed course Practical Application of Toxicology in Drug Development. The course, co-organised by the British Toxicology Society and the [...]
Professor Ruth Roberts Joins Bio Integrates Panel Professor Ruth Roberts, Co-founder and Director of ApconiX will join Professor Paul Stott, Chief Executive Officer of Seda Pharmaceutical Development Services, Dr Steve McConchie, Chief Executive Officer of Aptus Clinical and Dr Matt Cooper, Business Development & Marketing Director of National Institute [...]
Toxicological Sciences: From the Editor's Desk, Editor's Highlights One of the recent Editor's Highlights in Toxicological Sciences was a paper by Peters et al., on GI Barrier and Drug-induced Diarrhea, reviewed by Professor Ruth Roberts, an Associate Editor of Toxicological Sciences. As Ruth highlighted, attrition in drug discovery and [...]
