An Integrated Approach to cardiac safety and CiPA

Speakers: Dr Michael Morton from ApconiX and Richard Printemps from PhysioStim.

This was a Society of Toxicology Exhibited Hosted Session given in 2021.

This presentation will discuss why cardiac safety is so important during the drug discovery and the importance in this scenario of hERG ion channel and the more recent CiPA initiative. Ion channels as a cardiac safety liability, stem cell cardiomyocytes and ex-vivo heart studies will also be discussed and how they might be deployed in an integrated approach to cardiac drug safety

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