Guy Healing was recently selected from many applicants to join the panel of the UK register of toxicologists. The UKRT was created in 1993 in response to the need for international harmonization and mutual recognition of toxicologists and is sponsored by The Royal Society of Biology and the British Toxicology Society. By identifying professional toxicologists [...]
Jane Stewart recently lectured on Reprotoxicology within the Non Clinical Development module of the TOPRA MSc course. As the professional membership organisation for individuals working in healthcare regulatory affairs, TOPRA works with its members internationally to enable and promote excellence across the healthcare regulatory profession. This course, for healthcare regulatory professionals, was attended by students [...]
This poster, presented at the Gordon Research Conference in August 2017, concluded that: Target safety assessments: Provide expert assessment and interpretation of literature and available databases and are invaluable in identifying and avoiding target-related risks Inform target selection and/or prioritisation early in discovery Should contain the level of detail appropriate to the project stage Should [...]
Target Safety Assessment: Strategies and Resources, Chapter 12 of Drug Safety Evaluation Methods in Molecular Biology (vol 1641), was written by Dr Richard J Brennan, a Scientific Advisor at Sanofi in the United States. The chapter presents a summary of the information types and sources that should be investigated and approaches that can be [...]
ApconiX has a vacancy for a Research Scientist based at the BioHub, Alderley Park, UK ApconiX is an integrated toxicology and ion channel company that brings together a team of dedicated world-class experts to ensure that potential new medicines are safe for patients. We work with other companies, charities, academic institutions and government agencies across [...]
Sygnature Discovery recently hosted a lecture by Professor Ruth Roberts and Dr Michael Morton from ApconiX. Based at BioCity in Nottingham, Sygnature Discovery is the UK’s largest independent provider of integrated drug discovery resource and expertise. The theme of the lecture and subsequent debate with the attendees was 'Safety considerations in early chemical design: Challenges and [...]
Ruth Roberts is first author on one of Toxicological Sciences’ top 10% downloaded articles during the last 2 years. The paper, ‘Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward’ describes the challenges and opportunities in the development of biomarkers of neurotoxicity, a goal shared by scientists across academia, [...]
In February, APTrans signed a service agreement with Evgen Pharma to provide support to their lead program, SFX-01. Evgen Pharma is a clinical stage drug development company with projects in breast cancer and subarachnoid haemorrhage. APTrans is a consortium of companies based at the BioHub at Alderley Park, formed by ApconiX, Aptus Clinical and Seda [...]
ApconiX Associate Jane Stewart is first author on a manuscript in the DIA peer-reviewed journal “Therapeutic Innovation and Regulatory Science” (TIRS) that has received the DIA’s 2017 Author of the Year Award. This annual award honours the author of the most accessed and downloaded article in TIRS. The article ‘Birth Control in Clinical Trials: [...]
As we get ready for a busy and exciting 2017, it’s a good time to reflect on ApconiX’s first full year in business and share some notable highlights. In 2016 we were joined by several additional preclinical experts including Dr Guy Healing, Dr Damian Deavall, Dr Jane Barber, Dr Mike O’Donovan and Dr Peter Ballard [...]
