Ruth Roberts is first author on one of Toxicological Sciences’ top 10% downloaded articles during the last 2 years. The paper, ‘Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward’ describes the challenges and opportunities in the development of biomarkers of neurotoxicity, a goal shared by scientists across academia, government, and industry. The paper used the Health and Environmental Sciences Institute (HESI) framework to propose a consensus on the relative potential of currently described biomarkers of neurotoxicity and then assessed experimentally the utility of shortlisted biomarkers in a nonclinical model.
The project described in the well-cited 2015 paper is ongoing and the exciting data emerging will be submitted for publication later this year. Watch this space!