The official photographs are out to show that it was all smiles in San Antonio earlier this year when I received the 2018 Society of Toxicology (SOT) founders award. I was proud to be presented with the plaque by my good friend and colleague, Leigh Ann Burns Naas. Dr Burns Naas is SOT President as [...]
Ruth Roberts (ApconiX) and Emma Walker (Kings College London) attended the Royal Society of Biology President's Dinner May 2nd 2018 where they chatted with Stephen Benn about the great work he does as Vice-President of the Parliamentary and Scientific Committee and for the Society as their Director of Parliamentary Affairs. Professor Dame Julia Goodfellow succeeded [...]
ApconiX is delighted to welcome Dr Jane Barber who joins us from AstraZeneca. Jane, a dedicated drug discovery research scientist will work with the team of experts in nonclinical safety toxicology at ApconiX. Jane graduated from the University of Keele with a degree in Biology and Classical studies. After researching Molecular Parasitology and Vector Biology, [...]
We were delighted to sponsor the poster and drinks reception at the annual British Toxicology Society meeting April 2018. The posters were fascinating with lots of new data on topics such as differentiated pluripotent stem cells, predicting and avoiding drug-induced toxicity and characterisation of cardiac stem cells for assessment of cardiotoxicity. There were also some [...]
ApconiX enjoyed a double-billing at the recent ‘Predictive Toxicology in Discovery DMPK’ meeting hosted by Sygnature Discovery and Xenogesis in Nottingham. Ruth Roberts kicked off the event with the keynote address entitled ‘Roberts Derisking early drug projects Shortened Version March 2018’ (click the title for pdf). Mike Morton addressed the conference later on in [...]
Team ApconiX (Ruth Roberts, Richard Knight, Mike Morton, Paul Duffy and Claire Sadler) had a truly outstanding SOT2018 with great new science and great new contacts. Ruth Roberts was the proud recipient of the 2018 SOT Founders Award presented by SOT president Patti Ganey. Claire Sadler presented in a session on Elevator Pitch followed by [...]
Ruth Roberts, Richard Knight, Mike Morton, Paul Duffy and Claire Sadler will be at SOT2018. We’d love to talk to you about how ApconiX can add value to your projects through better decisions in drug project toxicology, target safety assessments and ion channel/hERG screening. Every project is unique and needs the guidance of experts to ensure [...]
Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study. Abstract: Neurotoxicity has been linked with exposure to a number of common drugs and chemicals, yet efficient, accurate, and minimally invasive methods to detect it are lacking. Fluid-based biomarkers such as [...]
Did you know that safety issues remain one of the main reasons why drug projects fail? Multiple publications over recent years have continued to highlight non-clinical safety/toxicity as the most frequent reason for project failure in drug development. For example, in a study of 605 projects from GSK, AstraZeneca, Ely Lilly and Pfizer, nonclinical toxicology [...]
Looking forward to seeing everyone at SOT 2018. Ruth Roberts will be the proud recipient of the 2018 SOT Founders Award at the Awards Ceremony on Sunday evening and Ruth and Claire Sadler will be presenting in the session on Elevator Pitches on Tuesday afternoon. Come and say Hi to Ruth, Richard Knight, Mike [...]
