ApconiX enjoyed a double-billing at the recent ‘Predictive Toxicology in Discovery DMPK’ meeting hosted by Sygnature Discovery and Xenogesis in Nottingham. Ruth Roberts kicked off the event with the keynote address entitled ‘Roberts Derisking early drug projects Shortened Version March 2018’ (click the title for pdf). Mike Morton addressed the conference later on in the day with a talk on ‘The Changing Face of Cardiovascular Safety Testing’. There was much discussion with a highly engaged audience on new challenges and successful strategies to identify and progress those projects with the highest probability of success. The key is to generate data early, while we still have choices in target and chemistry!