Improve Drug Project Success by Understanding Drug Target Safety Join Professor Ruth Roberts, Director and Co-founder, ApconiX Ltd, Dr Claire Sadler, Project Toxicologist, ApconiX and Dr Leigh Ann Burns Nass, President/Owner, Magnolia Toxicology Consulting, LLC in a live webinar on Thursday, October 1, 2020 at 11am EDT (4pm BST/UK) In [...]
Dr Kimberly Rockley's First Six Months at ApconiX Kimberly Rockley completed her PhD in the Division of Pharmacy at Durham University before joining us at ApconiX in June last year. Here she reflects on her first 6 months with the company. “Having gained a background in cancer biology, toxicology [...]
Acuity Target Safety Assessments: Knowledge is Power A thorough understanding of potential target-related effects is crucial to making the right choices in drug discovery. Experienced project toxicologists extract and interpret data from mouse knockouts, human gene mutations and known effects of modulators to determine the potential consequences of target inhibition or [...]
Working at ApconiX Phumzile Sikakana graduated from the University of Sheffield in January this year and was awarded a distinction in her master’s degree. Phum joined ApconiX in November last year and here reflects on her first 6 months with the company. "I was a recent biomedical science graduate [...]
ApconiX Welcomes Dr Russell Huby to the Team. ApconiX is delighted to welcome Dr Russell Huby to the team. Russell joins the team of experts in nonclinical safety toxicology at ApconiX and will be primarily working in the area of target safety assessments. Russell graduated from the University of [...]
ApconiX Opens a New Office in Sweden ApconiX is excited to announce the opening of our new office in Sweden. The subsidiary ApconiX AB will be located at AstraZeneca’s BioVentureHub in Gothenburg. ApconiX was formed by Dr Richard Knight, Dr Michael Morton and Professor Ruth Roberts in 2015 and [...]
ApconiX Welcomes Dr Karin Burnett to The Team ApconiX is delighted to welcome Dr Karin Burnett, an experienced project toxicologist with a broad knowledge of toxicology and chemical risk assessment in the pharmaceutical industry. Karin will join the team of experts in nonclinical safety toxicology at ApconiX, who cover all [...]
ApconiX Welcomes Phumzile Sikakana to The Team ApconiX is delighted to welcome Phumzile Sikakana who joins us straight from University. Phum, an enthusiastic new master's graduate will work with our team of experienced scientists on a variety of projects, including target safety reviews and in the ion channel screening [...]
ApconiX is delighted to welcome Dr Jane Barber who joins us from AstraZeneca. Jane, a dedicated drug discovery research scientist will work with the team of experts in nonclinical safety toxicology at ApconiX. Jane graduated from the University of Keele with a degree in Biology and Classical studies. After researching Molecular Parasitology and Vector Biology, [...]
This poster, presented at the Gordon Research Conference in August 2017, concluded that: Target safety assessments: Provide expert assessment and interpretation of literature and available databases and are invaluable in identifying and avoiding target-related risks Inform target selection and/or prioritisation early in discovery Should contain the level of detail appropriate to the project stage Should [...]
