Improve Drug Project Success by Understanding Drug Target Safety

Improve Drug Project Success by Understanding Drug Target Safety

Join Professor Ruth Roberts, Director and Co-founder, ApconiX Ltd, Dr Claire Sadler, Project Toxicologist, ApconiX and Dr Leigh Ann Burns Nass, President/Owner, Magnolia Toxicology Consulting, LLC in a live webinar on Thursday, October 1, 2020 at 11am EDT (4pm BST/UK)

In this free webinar, hosted by XTALKS, the speakers will explore data access and interpretation using case studies to demonstrate the target safety assessments value proposition, ultimately improving project success. Attendees will learn about managing hazard versus risk in drug projects and how knowledge of target biology can drive better decision-making and prioritization of research activities. They will also learn how to generate the tools to develop and implement risk-mitigation plans and how understanding drug target safety can improve drug project success.

At least 50 percent of drug safety failures are attributable to target-related effects. So, it makes sense to understand potential safety liabilities associated with a target early in projects, in order to anticipate and manage those issues before they arise.

A. target safety assessment (TSA) brings together public domain information (target homology, gene and protein expression profiles, transgenic and mutation phenotype data, competitor compounds) into a report that identifies and categorizes key risks by organ/tissue and by physiological functions. This systematic categorization is used as the basis of a risk mitigation plan with ranking of risks and potential next steps, presented as a Word document with embedded PowerPoint.

Join this educational webinar to learn how target safety assessments (TSAs) are used to determine the potential consequences of modulating a target and provide options on how to assess those risks. Experts will describe how we derive relevant insights from the vast amount of publicly available information to provide clients with a focused assessment of key risks, tailored for each individual project.

For more information or to register for this event, visit Improve Drug Project Success by Understanding Drug Target Safety.


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