Ruth Roberts (ApconiX) and Emma Walker (Kings College London) attended the Royal Society of Biology President's Dinner May 2nd 2018 where they chatted with Stephen Benn about the great work he does as Vice-President of the Parliamentary and Scientific Committee and for the Society as their Director of Parliamentary Affairs. Professor Dame Julia Goodfellow succeeded [...]
ApconiX is delighted to welcome Dr Jane Barber who joins us from AstraZeneca. Jane, a dedicated drug discovery research scientist will work with the team of experts in nonclinical safety toxicology at ApconiX. Jane graduated from the University of Keele with a degree in Biology and Classical studies. After researching Molecular Parasitology and Vector Biology, [...]
We were delighted to sponsor the poster and drinks reception at the annual British Toxicology Society meeting April 2018. The posters were fascinating with lots of new data on topics such as differentiated pluripotent stem cells, predicting and avoiding drug-induced toxicity and characterisation of cardiac stem cells for assessment of cardiotoxicity. There were also some [...]
Many companies involved in cancer drug research and development need to re-think their use of safety data in helping to bring new drugs to cancer patients. Dr Richard Knight of Alderley Park-based ApconiX told last month’s conference, Accelerating Cancer Drug Development – from target to patients, that greater focus on pre-clinical safety should be fundamental to [...]
ApconiX enjoyed a double-billing at the recent ‘Predictive Toxicology in Discovery DMPK’ meeting hosted by Sygnature Discovery and Xenogesis in Nottingham. Ruth Roberts kicked off the event with the keynote address entitled ‘Roberts Derisking early drug projects Shortened Version March 2018’ (click the title for pdf). Mike Morton addressed the conference later on in [...]
Team ApconiX (Ruth Roberts, Richard Knight, Mike Morton, Paul Duffy and Claire Sadler) had a truly outstanding SOT2018 with great new science and great new contacts. Ruth Roberts was the proud recipient of the 2018 SOT Founders Award presented by SOT president Patti Ganey. Claire Sadler presented in a session on Elevator Pitch followed by [...]
Ruth Roberts, Richard Knight, Mike Morton, Paul Duffy and Claire Sadler will be at SOT2018. We’d love to talk to you about how ApconiX can add value to your projects through better decisions in drug project toxicology, target safety assessments and ion channel/hERG screening. Every project is unique and needs the guidance of experts to ensure [...]
Why is Time Critical to hERG Screening Data? ApconiX has worked hard to optimise our processes and is now returning over 80% of hERG screening data back to clients within one week of compound receipt. This allows critical decisions to be made in medicinal chemistry on a full dataset [...]
Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study. Abstract: Neurotoxicity has been linked with exposure to a number of common drugs and chemicals, yet efficient, accurate, and minimally invasive methods to detect it are lacking. Fluid-based biomarkers such as [...]
Accelerating Cancer Drug Development -From target to patients, BioNow will be hosting this event at Alderley Park on the 27th of February 2018. Focusing upon the strengths in the discovery, development and manufacture of cancer medicines in the North of England through to commercialisation (patients), this event will highlight industry, academic and clinical strengths whilst [...]
