GRC – Cellular and Molecular Mechanisms of Toxicity


Dr Rhiannon Hardwick (BMS), Conference Chair, will be joined by Professor Heather Wallace, University of Aberdeen as Vice Chair of the Gordon Research Conference (GRC)  Cellular and Molecular Mechanisms of Toxicity – Modernized Approaches to Mechanistic Toxicology Investigations at the Proctor Academy, Andover, New Hampshire, United States between the 13th and 18th of August 2023.

Professor Ruth Roberts will lead the discussion during Session I: Artificial Intelligence in Toxicology and its Role in Decision Making on Monday the 14th of August.  Dr Heather Wallace will lead the discussion during Session VII: Early Career Investigators in mechanistic Toxicology on Thursday the 17th of August.

Cellular and Molecular Mechanisms of Toxicity Gordon Research Conference:

The Cellular and Molecular Mechanisms of Toxicity GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field.

Collaboration across the many areas of toxicology research including the environmental sciences and pharmaceutical and consumer product development, is critical for scientific advancement as scientists from academia, private industry and government strive to solve crucial public health problems.

The program aims to highlight interdisciplinary and integrative scientific partnership with featured session topics including functional genomics, environmental toxicant metabolism, impact of the cellular microenvironment on toxic responses, artificial intelligence in toxicology, modernization of developmental toxicity testing, and integration of new approach methodologies in risk assessment for multiple areas including neurotoxicity, mixtures, and new therapeutic modalities and also includes an early career investigator session featuring two trainees selected from the associated Gordon Research Seminar (GRS) along with emerging investigators in mechanistic toxicology from across the U.S. and abroad.


  • Keynote: Gene Essentiality and Functional Genomics for Mechanistic Toxicology
  • Artificial Intelligence in Toxicology and its Role in Decision Making
  • The Cellular Microenvironment in Tissue Health, Disease and Toxic Exposure Outcomes
  • New Modalities, Mechanisms and Methods in Neurotoxicity
  • Novel Mechanisms Regulating Environmental Toxicant Metabolism
  • Modern Approaches in Developmental Toxicity Testing
  • A Mechanistic View of Mixtures Toxicology from Human Health to Ecological Health
  • Early-Career Investigator Presentations
  • Keynote: Mechanisms of Protein Degradation by Immunomodulatory Drugs and Targeted Protein Degraders

Click here for preliminary details of the Cellular and Molecular Mechanisms of Toxicity GRC programme.

The detailed program will be available by April 15, 2023.Click here for updates 

Applications for this meeting must be submitted by July 16th, 2023. Click here to apply

This GRC will be held in conjunction with the Cellular and Molecular Mechanisms of Toxicity Gordon Research Seminar (GRS).


The Gordon Research Seminar on Cellular and Molecular Mechanisms of Toxicity “Exploring Frontiers in Translational Toxicology: Linking Mechanistic Research to Real-World Applications” will be held on the 12th and 13th August 2023 and provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The seminar will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS, either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The seminar chair will select speakers from abstracts submitted by May 7, 2023.

Gordon Research Seminars are 2-day meetings which take place on the Saturday and Sunday just prior to the start of the associated GRC. The GRS opens with a 1-hour introductory session on Saturday afternoon, followed by a poster session, dinner and a 2-hour session in the evening. Sunday morning begins with breakfast and is followed by another 2-hour session, a second poster session, and lunch. A final 1-hour session takes place just after lunch, and the associated GRC begins later that evening.

For more information visit the GRS website