Join Professor Ruth Roberts for the next science webinar in the Alderley Park Science Seminar Series:
Science-Driven Design of the Preclinical Strategy: Case by Case
Ruth will present lessons learned from >20 years’ experience in the pharmaceutical industry focusing on attrition, prediction and the challenges posed by nonclinical to clinical concordance. Several case studies that focus on science-driven design will be shared for discussion. Chemical liabilities should be eliminated early in discovery while there are still options in chemistry. Equally important is a thorough understanding of potential target-related risks and their likelihood of occurrence. The triple challenge of attrition, concordance and the 3Rs should drive us to take a longer term, strategic approach to drug discovery and safety testing. New technologies such as micro physiological systems (MPS), artificial intelligence and big data all offer opportunities to do things differently. But are we ready for change? These issues and potential solutions will be presented for discussion.
Click here to register Science-Driven Design of the Preclinical Strategy: Case by Case