Long interspersed nuclear elements(Line-1 orL1s) account for~17% of the human genome. While the majority of human L1s are inactive, ~80–100 elements remain retrotransposition competent and mobilise through RNA intermediates to different locations within the genome. De novo insertions of L1s account for polymorphic variation of the human genome and disruption of target loci at their new location…
Author: Bojang, P., Anderton, M., Roberts R. and Ramos, K (2014)
