You data turnaround time is incredibly good and it really helps us track the SAR and progress our compounds in a rapid and efficient manner. Thanks ApconiX for your wonderful support to Bugworks

"We would not be here without your excellent input and help.  You and ApconiX have been absolutely fantastic.  Great planning and execution.....strong, straightforward communication.....pragmatic and a strong sense of team"

The challenge The U.S. Food and Drug Administration's National Center for Toxicological Research (NCTR) is a global resource for collaboration providing consultation, training, and innovative scientific solutions in support of FDA's mission to improve public health. Within NCTR, The Division of Bioinformatics and Biostatistics is developing bioinformatics methodologies and standards to support FDA research and [...]

The challenge Redx Pharma is a drug discovery and development company focused on creating new drugs for areas of unmet medical need such as cancer and immunology.  As their portfolio rapidly matured, Redx recognised a need for expert safety input as well as ion channel screening data, to develop high quality clinical candidates. The solution [...]

The challenge Our client had identified a clinical candidate aimed at a novel tumour target, with promising activity against a range of cancers.  Upon completion of suitable GLP toxicity studies, the company intended to move into Phase I in patients, in combination with chemotherapy. There were a number of pressing issues, including choice of [...]

The challenge Blueberry Therapeutics is a dermatology biotech company developing innovative topical drugs for a range of diseases, using a novel ‘nano-delivery’ platform. This technique significantly enhances the penetration of drugs into cells and tissues. Apconix was set the challenge to provide guidance on the most appropriate nonclinical safety studies needed to support the [...]

“It has been a tremendous pleasure to work with Ruth @ApconiX for the past year. Her in-depth knowledge in toxicology in general and drug discovery/development in specific has contributed significantly to my division's research in the area of drug-induced liver injury and in vitro to in vivo extrapolation. I am expecting much great science [...]

"I have had the privilege of knowing Dr. Ruth Roberts for 3 years. I immensely enjoyed discussing the role of ILSI-HESI in the US and in the Europe with Ruth. With her vast experience in the field of Toxicology, especially in ion-channel, she is blessed with innovative thinking in nonclinical toxicology and safety science. [...]

"ApconiX provided us exactly the right insight we needed, in a timely and professional fashion. They were attentive to our needs, flexible on timing, and easy to work with."