FDA NCTR

2018-08-08T08:05:51+00:00

The challenge The U.S. Food and Drug Administration's National Center for Toxicological Research (NCTR) is a global resource for collaboration providing consultation, training, and innovative scientific solutions in support of FDA's mission to improve public health. Within NCTR, The Division of Bioinformatics and Biostatistics is developing bioinformatics methodologies and standards to support FDA research and [...]

Redx Pharma

2018-08-08T07:51:17+00:00

The challenge Redx Pharma is a drug discovery and development company focused on creating new drugs for areas of unmet medical need such as cancer and immunology.  As their portfolio rapidly matured, Redx recognised a need for expert safety input as well as ion channel screening data, to develop high quality clinical candidates. The solution [...]

Blueberry Therapeutics

2018-08-07T23:24:36+00:00

The challenge Blueberry Therapeutics is a dermatology biotech company developing innovative topical drugs for a range of diseases, using a novel ‘nano-delivery’ platform. This technique significantly enhances the penetration of drugs into cells and tissues. ApconiX was set the challenge to provide guidance on the most appropriate nonclinical safety studies needed to support the [...]

FDA

2018-07-25T14:47:24+00:00

“It has been a tremendous pleasure to work with Ruth @ApconiX for the past year. Her in-depth knowledge in toxicology in general and drug discovery/development in specific has contributed significantly to my division’s research in the area of drug-induced liver injury and in vitro to in vivo extrapolation.  I am expecting much great science [...]

Redx

2018-07-25T14:43:44+00:00

“ApconiX has provided hERG data to Redx Pharma from June 2016 to help support our discovery projects. Data turnaround times over this period have been rapid (under 1 week) and this has been critical in progressing projects quickly; outsourcing the assay with this turn-around has had no impact on our "design-make-test" cycle times. Additionally, ApconiX’s approach is very collaborative providing [...]

Blueberry Therapeutics

2018-08-07T12:02:49+00:00

"The support that we received from the ApconiX team has been excellent and they have helped us both in developing our nonclinical safety thinking and in providing direct support for the clinical trial application. We’re looking forward to continuing our collaboration as we progress our exciting new medicines into later-stage development and hopefully the [...]

Evgen Pharma

2018-07-15T12:52:58+00:00

“We are delighted to have found a flexible way to access specialist technical expertise and operational support to complement our existing internal capabilities to support the ongoing development of our lead product, SFX-01.  We selected this excellent group of providers as our partners as they have a proven track record of working well together [...]