What Else We Do

Current and Future Opportunities for Improving Translational Safety

We are delighted to celebrate the third year of our Drug Safety Forum, providing a platform for nonclinical and clinical communities to engage with current safety science and offer a future perspective. We focus on new theoretical and experimental approaches to translational safety science.

The central themes of the forum are two-fold; what more can we achieve and what new models can we access that helps us to better understand what will happen in the clinic. Knowing in vivo testing is still essential, what supplementary data can be gathered to give us a clearer view of clinical safety?

Celebrating 10 Years of Trading

ApconiX celebrates 10 years of trading this month (July 2025).  As well as a party we have produced a podcast of the journey that started with AstraZeneca announcing the closure of the R&D facilities in Alderley Park. and taking us to a team of over 100 scientists. “We’ve built a fantastic team of talented people, people with vast experience in the industry through to a younger generation of scientists, working all over the world to bring safer medicines to patients quicker”.

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iSLA in vitro Seizure Liability Assay

ApconiX is a team of world-renowned nonclinical safety experts. Our aim is to support organisations to bring safe and effective drugs to market and advance the science of drug safety. Our lab has a strong focus on ion channel screening, and ApconiX has always carried novel research.

Our in vitro seizure liability assay iSLA was developed over 3 years and launched in July 2022.  The story of it’s development is a fascinating insight into how research and development works.

What our Excellent NET Promotor Score says about the services we deliver for our customers

Net Promoter Score (NPS) is a widely used measure of customer satisfaction. A score above 0 is good and a score above 50 is excellent. We measure NPS every 6 to 12 months, and we were delighted that the last survey gave a score of 100. The aggregate score was 77.

Whats Happening Now net promoter | ApconiX
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Tubular Cells

Have you ever wondered what brain cells sound like?  A very talented group of people turned the MEA electrical signals generated by our in vitro seizure liability assay (iSLA) into music.

Listen to the music and the podcast of how the it was created.

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A pharma strategy game that challenges YOU to achieve maximum value through investment in novel new medicines.

Portfoli-oh! originated from our day jobs in the Pharma industry where each drug project is an exciting challenge of balancing resources across multiple projects with the end game of approval always in mind. Along the way there are multiple challenges and opportunities and a few surprises against an ever-evolving corporate strategy. As a player, you can maximise your chances of success although there is an element of luck in the cards…

Whats Happening Now poster | ApconiX

Our Research

We love collaborating on complex areas of science such as problem solving and on the use of data science in drug discovery.  Check out our multitude of papers, videos and posters on, drug safety, TSAs, iSLA (our in vitro seizure liability assay), immunotoxicology, ion channel research and many more areas of interest.

NAM’s RRR’s & Sustainability

At ApconiX, we are passionate about continuous improvement.  We have developed an innovative NAM to tackle seizure liability in drug discovery and are at the forefront of responsible, science-led study design. We are also contributing to the HESI NAMs and the NC3Rs expert working groups such as NAMs and species selection.  We are working to minimise the use of resources such as plastics and serum in our ion channel laboratory.

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Coming soon

‘Snakes & Ladders’ on-line Drug Discovery game

Experience the ‘ups and downs’ of Drug discovery in this fun to play ‘Snakes & Ladders’ on-line game! Originally a board game, a digital board game seemed a more accessible option.

What Next?!

We’re not totally sure what ideas we’ll have next.  Watch this space.  Join our mailing list and we’ll keep you to to date.

Whats Happening Now snake | ApconiX

Testimonials

‘”I have found the team to be very responsive to requests and I feel that they are part of the team delivering to our project.”
‘”I have found the team to be very responsive to requests and I feel that they are part of the team delivering to our project.”
“I am very impressed with the ApconiX TSA. In my experience, it is a remarkably comprehensive and well-structured resource that surpasses anything I have encountered elsewhere. The content is detailed and informative, yet presented in a way that is accessible to both technical and non-technical audiences. The logical flow and clear organization make it easy to follow, and the reference section provides a valuable springboard for further exploration.”
“I am very impressed with the ApconiX TSA. In my experience, it is a remarkably comprehensive and well-structured resource that surpasses anything I have encountered elsewhere. The content is detailed and informative, yet presented in a way that is accessible to both technical and non-technical audiences. The logical flow and clear organization make it easy to follow, and the reference section provides a valuable springboard for further exploration.”
“Really helpful to be able to consult with a range of toxicologists with years of experience in real project situations. really enjoying the support and getting value from the support given by Claire Sadler and Jane Stewart specifically.”
“Really helpful to be able to consult with a range of toxicologists with years of experience in real project situations. really enjoying the support and getting value from the support given by Claire Sadler and Jane Stewart specifically.”
“ApconiX provides all round excellent service.”
“ApconiX provides all round excellent service.”
‘Very efficient and responsive support’
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“With many thanks- this target safety assessment was exactly what we needed and we are very pleased with the quality of the work that went into this”
“With many thanks- this target safety assessment was exactly what we needed and we are very pleased with the quality of the work that went into this”
“ApconiX is trustworthy and deliver quality data in a timely manner.”
heading section

‘”I have found the team to be very responsive to requests and I feel that they are part of the team delivering to our project.”

VP of Biology

“I am very impressed with the ApconiX TSA. In my experience, it is a remarkably comprehensive and well-structured resource that surpasses anything I have encountered elsewhere. The content is detailed and informative, yet presented in a way that is accessible to both technical and non-technical audiences. The logical flow and clear organization make it easy to follow, and the reference section provides a valuable springboard for further exploration.”

Toxicologist

“Really helpful to be able to consult with a range of toxicologists with years of experience in real project situations. really enjoying the support and getting value from the support given by Claire Sadler and Jane Stewart specifically.”

VP of Discovery, DMPK and Safety

“ApconiX provides all round excellent service.”

Jamie Bilsland, Chief Scientific Officer

‘Very efficient and responsive support’

Analytical Chemistry Manager

“With many thanks- this target safety assessment was exactly what we needed and we are very pleased with the quality of the work that went into this”

Head of Translational Science

“ApconiX is trustworthy and deliver quality data in a timely manner.”

Senior Director – Chemistry