Epigenetics – Relevance to Drug Safety Science. Toxicology Research 1 3-6.
Epigenetics describes the study of heritable changes in gene expression that occur in the absence of a change to the DNA sequence. Specific patterns of epigenetic signatures can be stably transmitted through mitosis and cell division and form the molecular basis for developmental stage- and cell type-specific gene expression. Associations have been observed that endogenous and exogenous stimuli can change the epigenetic control of both somatic and stem cell differentiation and thus influence phenotypic behaviours and/or disease progression…
By Chloe Atkinson|2022-11-28T14:11:57+00:00June 17th, 2021|Comments Off on Epigenetics – Relevance to Drug Safety Science. Toxicology Research 1 3-6.