Can Transcriptomic Profiles from Cancer Cell Lines be Used for Toxicity Assessment? Toxicological Sciences, Chemical Research in Toxicology. 23 343-367.
In vitro toxicogenomics (TGx) has the potential to replace or supplement animal studies. However, TGx studies often suffer from a limited sample size and cell types. Meanwhile, transcriptomic data have been generated for tens of thousands of compounds using cancer cell lines mainly for drug efficacy screening. Here, we asked the question of whether these types of transcriptomic data can be used to support toxicity assessment…
By Chloe Atkinson|2022-11-28T14:08:37+00:00June 17th, 2021|Comments Off on Can Transcriptomic Profiles from Cancer Cell Lines be Used for Toxicity Assessment? Toxicological Sciences, Chemical Research in Toxicology. 23 343-367.