Aina Mogas Barcons

2024-02-29T10:58:02+00:00

Meet The Team

Aina Mogas Barcons | ApconiX

Aina Mogas Barcons

PhD

Aina is a neuroscientist with a biology background, specialising in neurodegenerative diseases.  Graduating from the Universitat Aut`onoma de Barcelona (Spain) with a  BSc in Biology and a MSc in Neuroscience, Aina went on to research spinal cord models for her Ph.D. in Neural Tissue Engineering at the Keele University (UK).  Fluent in both Spanish and Catalan, Aina is passionate about science communication and looks forward to making a contribution to the world of scientific communication, globally.

Heather Brown

2024-02-19T16:39:39+00:00

Meet The Team

Heather Brown | ApconiX | Early Career

Heather Brown

Heather graduated from the University of York with a BSc in Biology.  She enjoys data analysis and the representation of results and her final project dissertation was a review of in silico data and how it predicted laboratory findings.  Working on immunotoxicology capability development with Dr Sean Hammond, Heather is a conscientious and enthusiastic scientist, with a systematic approach to scientific issues.

Read more here Heather Brown

Leah Worthington

2024-02-19T16:39:41+00:00

Meet The Team

Leah Worthington | ApconiX | Early Career

Leah Worthington

Leah graduated from the University of Birmingham with a degree in Biological Sciences.  Her interests are in ecology, genetics and disease.  Within the Target Safety Assessment team, she will be working on bioinformatics for TSAs, as well as gaining an overview of the whole process.  Leah’s broad biological knowledge and adaptability brings valuable capability and flexibility to the team

Read more here Leah Worthington

Abigail Walker

2023-10-02T14:56:50+01:00

Meet The Team

Abigail Walker

Abigail Walker

MSc

Abigail Walker is a scientific writer with experience in toxicology, neuroscience, neurobiology and nutrition, having graduated from the University of Glasgow with a BSc and MSc in Neuroscience.  A keen communicator, she enjoys expanding her knowledge base, drawing out the key points in complex scientific subjects and working collaboratively in teams.

Helen Garside

2022-10-20T15:49:31+01:00

Meet The Team

Dr Helen Garside

Helen Garside

PhD

Helen has over 10 years of experience in the pharmaceutical industry focused on predictive and mechanistic toxicology.  She has expertise in early project toxicology gained through roles in discovery safety and safety pharmacology, supporting projects across multiple therapy areas. Helen has a passion for collaborative working and applying the latest technology to toxicology.

Sean Hammond

2023-01-10T15:24:19+00:00

Meet The Team

Dr Seam Hammond

Sean Hammond

PhD

Sean holds a PhD in immuno-pharmacology from the University of Liverpool, focused on developing experimental and conceptual means to address T-cell mediated hypersensitivity reactions. He has long-standing links with drug safety research at Liverpool where he received the Syngenta prize for Pharmacology at degree level and where he maintains an academic profile. He has several publications focused on the immuno-toxicological aspects of small molecular weight compounds and immune-checkpoint inhibitors. Sean particularly values working with inter-disciplinary experts to drive rational, data-led decision making in drug development projects.

Read more about Dr Sean Hammond

Angela Stokes

2022-10-20T15:53:36+01:00

Meet The Team

Angela Stokes

Angela Stokes

MSc CSci CChem FRSC FTOPRA

Angela has a strong scientific background in chemistry, pharmacology and toxicology and over 30 years of regulatory affairs experience in medicinal product and medical device development.   She has extensive experience of ICH, FDA and Committee for Medicinal Products for Human Use (CHMP) guidelines for a wide range of pharmaceutical products, and the International Organization for Standardization (ISO) standards for medical devices, in vitro diagnostics and quality systems. She has been influential in regulatory affairs training and mentoring and is a Fellow of The Organisation for Professionals in Regulatory Affairs (TOPRA) and a Fellow of the Royal Society of Chemistry. Angela was the winner of the 2015 TOPRA Award for Contribution and 2020 TOPRA Award for Inspiration.  Angela’s knowledge, breadth of experience in regulatory affairs, toxicology and pharmacology abilities and strategic approach aligns with and supports the toxicology group in ApconiX.

Karen Featherstone

2022-10-20T15:54:57+01:00

Meet The Team

Dr Karen Featherstone

Karen Featherstone

PhD

Karen is a Medical Writer with extensive experience in communicating health economics and outcomes research (HEOR) through a range of market access materials. Having worked within a global contract research organisation, she has a track record of delivering high quality, evidence-based materials to clients from across the pharmaceutical industry (from the top ten global pharmaceutical companies to small biotechnology companies) and across multiple disease areas, including infectious diseases and inflammatory disorders, cancer and rare genetic disorders. Karen has a comprehensive understanding of the core needs and challenges in gaining drug reimbursement and enjoys using her broad scientific knowledge to provide solutions to these challenges.

James Sidaway

2022-10-20T15:57:25+01:00

Meet The Team

Dr James Sidaway

James Sidaway

PhD

James is an experienced and innovative toxicologist having worked for over 20 years in the pharmaceutical industry with AstraZeneca and as an independent consultant. As a molecular-investigative toxicologist he helped resolve safety issues for a wide range of drug discovery and development projects across the major therapy areas. He has also developed advanced in vitro models for organ toxicity screening, pioneered the application of novel technology and informatics platforms and has a strong track record of delivering Target Safety Assessments.  James (also known as Sid)  has a real interest in solving mechanisms of drug toxicity and is energised by working collaboratively in industry, academic and commercial settings.

Read more here

Blueberry Therapeutics

2021-06-10T14:51:59+01:00

Blueberry Therapeutics

The challenge

Blueberry Therapeutics is a dermatology biotech company developing innovative topical drugs for a range of diseases, using a novel ‘nano-delivery’ platform. This technique significantly enhances the penetration of drugs into cells and tissues. ApconiX was set the challenge to provide guidance on the most appropriate nonclinical safety studies needed to support the clinical development of Blueberry’s new treatments for fungal infection.

The solution

We worked closely with Blueberry scientists to develop an innovative strategy to support the initiation of clinical studies on their lead compound. We started by identifying the specific scientific questions that needed to be addressed and focusing on the data needed to answer them. By utilising existing information from numerous sources, we were able to build a case to present to regulatory agencies that sufficient evidence was already available to support the safe use in clinical studies.

The benefit

By performing a systematic analysis of published data, we developed a clear scientific rationale to support the proposed clinical trial design, without the need for further nonclinical studies to support ‘First time in Man’ testing.

The outcome

This work was discussed at a successful face-to-face meeting with European regulators resulting in approval for Blueberry to begin clinical testing of this novel therapeutic agent.

The Testimonial

“The support that we received from the Apconix team has been excellent and they have helped us both in developing our nonclinical safety thinking and in providing direct support for the clinical trial application. We’re looking forward to continuing our collaboration as we progress our exciting new medicines into later-stage development and hopefully the clinic”

Dr. David Cook. Chief Scientific Officer, Blueberry Therapeutics
Go to Top