Redx Pharma Announces First Patient Dosed in Phase 1/2a

Redx Pharma has commenced a Phase I study for a novel cancer treatment at The Christie in Manchester. The compound, RXC004, is a novel, oral, potent small molecule Porcupine inhibitor, and targets the Wnt pathway that is implicated in the maintenance of cancer stem cells. ApconiX were proud to work with our Redx colleagues in [...]

By | 2018-02-14T10:01:35+00:00 February 13th, 2018|Alliances, Expertise, News, Toxicology, Uncategorised|0 Comments

Magic Mushrooms May Treat Depression

This recent article in the Sunday Times discusses how an extract of magic mushrooms may be able to make significant improvements in the treatment of severe depression. We were delighted to bring ApconiX's drug project toxicologist expertise to the team of experts working with COMPASS Pathways to find a safe, efficient and effective route into [...]

By | 2018-02-17T08:10:06+00:00 February 13th, 2018|Alliances, Expertise, News, Toxicology|0 Comments

Collaboration and Competition: Ethics in Toxicology

Two of the biggest ethical challenges in pharmaceutical toxicology are the use of animals in testing and the high safety-related attrition rates in new drug development.  Yet very little is invested in these two fields compared with investment in new efficacy models, new disease targets and new technologies.  How can this be addressed?  In this [...]

Ruth A Roberts receives 2018 SOT Founders Award

Ruth A. Roberts, PhD, ATS, FBTS, ERT, FRSB, FRCPath, ApconiX, Alderley Edge, United Kingdom, is the recipient of the Society of Toxicology (SOT) 2018 Founders Award for 'outstanding leadership in fostering the role of toxicological sciences in safety decision-making'. Dr. Roberts is chair and director of drug discovery at the University of Birmingham, United Kingdom, [...]

By | 2018-01-31T16:35:29+00:00 January 31st, 2018|Uncategorised|0 Comments

ApconiX named start up of the year!

We were delighted to be named 2017 Start Up Start-Up of the Year by BioNow, the northern England bio-medical and life sciences membership organisation. It's been an outstanding year for ApconiX with more than 60 clients across the UK, US and Europe including Pfizer, UCB and Gilead, as well as bio-techs, start-ups and university spin-outs. [...]

By | 2017-12-11T13:45:35+00:00 December 11th, 2017|Ion Channels, Northern Power House, Toxicology|0 Comments

Guy Healing to join the UK Register of Toxicologists Panel!

Guy Healing was recently selected from many applications to join the panel of the UK register of toxicologists www.toxreg.org.uk.    The UKRT was created in 1993 in response to the need for international harmonization and mutual recognition of toxicologists and is sponsored by The Royal Society of Biology and the British Toxicology Society. By identifying [...]

By | 2017-11-02T15:09:44+00:00 November 2nd, 2017|Uncategorised|0 Comments

Jane Stewart lectures on the TOPRA MSc course

Jane Stewart recently lectured on Reprotoxicology within the Non Clinical Development module of the TOPRA MSc course.  As the professional membership organisation for individuals working in healthcare regulatory affairs, TOPRA works with its members internationally to enable and promote excellence across the healthcare regulatory profession. This course, for healthcare regulatory professionals, was attended by students [...]

By | 2017-10-09T16:26:54+00:00 October 9th, 2017|Expertise, Reprotoxicology, Toxicology|0 Comments

Sygnature Discovery forms a strategic alliance with ApconiX

02 October 2017 – Nottingham and Alderley Park, UK – Sygnature Discovery, the UK's largest independent provider of integrated drug discovery resource and expertise, has announced it is to work in partnership with ApconiX, experts in non-clinical safety strategies and ion channel screening, to offer a broader range of drug discovery services. Dr Paul Clewlow, [...]

By | 2017-10-03T12:36:34+00:00 October 3rd, 2017|Uncategorised|0 Comments

ApconiX announce their alliance with PhysioStim.

The European Centre of Excellence for preclinical cardiovascular electrophysiology. The ApconiX team is pleased to announce their alliance with PhysioStim to create a new Centre of Excellence dedicated to cardiac safety studies. Both companies team up to offer a complete range of services in nonclinical cardiovascular electrophysiology. ApconiX, based at Alderley Park in the U.K. [...]

By | 2017-09-21T18:48:11+00:00 September 21st, 2017|News, Publication|0 Comments